Introduction: Hepatitis C virus is an RNA virus in the flavivirus family. Due to high hospitalization and frequent contact with needle diabetic patients are at greatest risk for HCV. Objective: To assess the seroprevalence of HCV and to identify associated factors among Type II Diabetic patients in Adigrat, Ethiopia. Method: A hospital based cross sectional study was conducted. Blood sample (5 ml) was collected and centrifuged. Using rapid antibody screening test Anti-HCV was determined from serum sample. Data was entered in to SPSS version 21 for final analysis. A bivariate and multivariate analysis was performed to identify factors related with HCV. Result: Out of the total study participants 22 (5.5%) of them were positive to HCV. HCV transmission is 12.5 times more likely by blood transfusion (95% CI of 1.61-96.22 P=0.016). Similarly, having surgical procedures increased HCV risk by 35 times (95% CI 5.94-157.24, P=0.00). Conclusion: The study confirmed a lower rate of HCV in Type II DM patients in Adigrat than previous study in Ethiopia. The present study recommends screening for HCV among Type II DM patients with operation or those having blood transfusion. HCV awareness and prevention campaign for all chronic DM patients are encouraged.
