Floating microsphere as novel approach drug delivery system

The present study was carried out to develop Saxagliptin drug delivery System in the form of microsphere dosage form of Saxagliptin by using EC and HPMC and thereafter formulating the formulation. From the study it is observed that formulation act as prolonged dosage form. As the stirring speed increased the size of microsphere decreases and increases the released rate drug. The prepared microsphere of saxagliptin also gave good percent yield, drug entrapment and Invitro release. The microspheres of F3 batch were found to be satisfactory in terms of\ percent yield, percent drug entrapment and In-vitro release.