Background of Study: Abnormal increase in fasting blood sugar, blood pressure, waist circumference, body mass index and some electrolytes are known to increase the risk of early cardiovascular event. Aim and Objectives: This study investigated the relationship between blood pressure, anthropometric variables, urine electrolytes and fasting blood sugar in students of College of Health Sciences, Nnewi. Material and Methods: A total of fifty (50) students were recruited in the study. All the parameters were measured using standard methods. Results: Results obtained were subjected to statistical analysis and results presented as mean±SD. The results show that the male subjects have a significantly lower (P<0.05) waist circumference and higher systolic blood pressure (P<0.05) compared to the female subjects. There was also a positive and significant correlation between urine potassium and systolic blood pressure (P=0.015) and diastolic blood pressure (P=0.04) in the male subjects. Conclusion: The results show that fasting blood sugar did not significantly correlate with all the parameters in both subjects. It can be concluded that the subjects’ waist circumference and systolic blood pressure could be the major predisposing factors to the subjects having cardiovascular diseases.