It belongs to a class of beta-blockers that is used to treat hypertension (high blood pressure) and angina (chest discomfort). The current research focusses mainly on the development of analytical and bioanalytical procedures, as well as the various techniques developed for the estimate of etoricoxib, whether in bulk or pharmaceutical dose form. Because they enable us to use sophisticated analytical techniques to acquire both qualitative and quantitative results, analytical methods are essential for determining compositions. Metoprolol succinate can be analyzed using spectroscopic, electrochemical, chromatographic, or hyphenated methods. These techniques minimize the effects of crucial process parameters on accuracy and precision while also assisting in their comprehension. The development of analytical methods is necessary to meet regulatory requirements and maintain high standards for the quality of commercial products. Standards and processes for granting approval, authentication, and registration have been established by regulatory bodies in a number of countries in response to the reference. The purpose of bioanalytical techniques is to measure the amount of a medication, metabolite, or common biomarker in a variety of biological fluids, such as tissue extracts, serum, urine, and saliva.