Background: Rhinocerebral mucormycosis is a complex and fatal infection typically affecting diabetic or immunocompromised patients. In most cases, infection is caused by inhalation of fungal spores. Material and methods: Survival rate of patients is moderately high 75% and Mortality rate is 25% in our series due to early diagnosis and treatment with aggressive sugar control, repeated debridement and antifungal therapy. Results: In this case series, 32 cases with rhinocerebral mucormycosis were presented. The etiologic agents and other survival and Mortality factors of mucormycosis in 32 Patients were isolated and identified by sequence analysis and data were registered and presented. Conclusion: In patients with mucormycosis, early detection, surgical excision and appropriate debridement, suitable antifungal therapy, and control of risk factors like diabetes mellitus are the main parameters of successful management of this lethal infection.